New disguises for an old channel: MaxiK channel ?-subunits

Orio, P; Rojas P.; Ferreira, G; Latorre R.

Keywords: sequence, chemistry, acid, muscle, fiber, variability, tertiary, animals, cells, ion, biology, protein, cell, gene, conductance, structure, channel, chain, calcium, mechanism, beta, physiology, family, channels, potassium, genetics, regulation, rna, molecular, review, data, article, chromaffin, large-conductance, cochlea, function, smooth, genetic, code, hearing, animal, metabolic, amino, nonhuman, Muscle,, neurosecretion, activated, Structure,, regulatory, tone, splicing, Channels,, Large, Calcium-Activated, slowpoke

Abstract

Ca2+-activated K+ channels of large conductance (MaxiK or BK channels) control a large variety of physiological processes, including smooth muscle tone, neurosecretion, and hearing. Despite being coded by a single gene (Slowpoke), the diversity of MaxiK channels is great. Regulatory ?-subunits, splicing, and metabolic regulation create this diversity fundamental to the adequate function of many tissues.

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Título según SCOPUS: New disguises for an old channel: MaxiK channel ?-subunits
Título de la Revista: NEWS IN PHYSIOLOGICAL SCIENCES
Volumen: 17
Número: 4
Editorial: NEWS IN PHYSIOLOGICAL SCIENCES
Fecha de publicación: 2002
Página de inicio: 156
Página final: 161
Idioma: English
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036667281&partnerID=q2rCbXpz
Notas: SCOPUS