Control of bleeding in cancer

Pereira J.

Keywords: disorder, acid, proteins, silver, compression, heart, therapy, thromboembolism, diarrhea, complex, plasma, bladder, inflammation, blood, cell, chemotherapy, cocaine, risk, infarction, disease, invasion, transplantation, patient, deficiency, treatment, thrombocytopenia, cancer, endoscopy, gastrointestinal, embolism, coagulation, formaldehyde, humans, invasiveness, artery, glue, lung, nitrate, human, agents, anticoagulants, anticoagulant, bradycardia, hypersensitivity, transfusion, hemorrhage, edema, agent, skin, radiotherapy, neoplasms, infusion, antiinflammatory, thrombosis, nausea, headache, urinary, drug, review, vomiting, mucosa, hyponatremia, fresh, factor, tachycardia, k, recombinant, beam, prothrombin, hypotension, tract, concentrate, vein, antineoplastic, epistaxis, frozen, vitamin, acute, artificial, ulcer, metrorrhagia, warfarin, assessment, systemic, tendency, bleeding, neoplasm, paraproteinemias, stem, sucralfate, therapeutic, anaphylaxis, techniques, group, subarachnoid, prostaglandin, use, accident, factors, mucositis, fibrin, continuous, response, hemophilia, proctitis, priority, desmopressin, journal, Von, effect, side, Willebrand, activated, nonsteroid, Cerebrovascular, thrombocyte, clotting, fibrinolytic, e2, f2, vagina, acetylsalicylic, external, indication, hematopoietic, adrenalin, tranexamic, Antifibrinolytic, Embolization,, Hemostatics, antithrombocytic, 7a, flushing, cryoprecipitate, unspecified, hemostatic, VIIa, aminocaproic, dysproteinemia, hypervolemia

Abstract

Clinically significant bleeding occurs in approximately 10% of the patients with advanced cancer [1]. Massive bleeding from the nose, pharynx, lung, or gastrointestinal tract constitutes a major challenge; however, it is difficult to predict who will have a serious bleeding event requiring special management and interventions. Bleeding in patients with cancer may present as a localized bleeding diathesis, more often as a result of local injury by tumor invasion or as a generalized hemorrhagic diathesis caused by thrombocytopenia, platelet dysfunction, coagulation factor deficiencies, presence of inhibitors or increased fibrinolysis. Mild persistent bleeding can be distressing for the patient, family members and caregivers; however, catastrophic massive bleeding may also occur, demanding urgent therapeutic intervention. © 2009 Springer-Verlag US.

Más información

Título de la Revista: Cancer Treatment and Research
Volumen: 148
Editorial: Springer
Fecha de publicación: 2009
Página de inicio: 305
Página final: 326
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-77953665760&partnerID=q2rCbXpz