LOCATION, ORIENTATION AND DYNAMICS OF TWO MOLECULES WITH MITOCHONDRIAL ACTIVITY DISSOLVED IN ANIONIC LYOMESOPHASE: A ²H-NMR AND MD STUDY

BAHAMONDE-PADILLA, VÍCTOR E; MARTINEZ-CIFUENTES, MAXIMILIANO; MUÑOZ-MASSON, DANIEL; Ruiz, Alvaro; Ahumada, Hernan; Araya-Maturana, Ramiro; Soto?Delgado, Jorge; WEISS-LÓPEZ, BORIS E

Abstract

4,4-Dimethyl-5,8-dihydroanthracene-1,9,10(4H)-trione (Q1) and 9,10-Dihydroxy-4,4-dimethyl-5,8-dihydro-1(4H)-anthracenone (Q2), two molecules that inhibit cancer cell respiration, were selectively deuterated and dissolved in an anionic discotic nematic lyotropic liquid crystal (dnllc) solution. The solution provides a magnetic field oriented anisotropic medium, where the location, average orientation and dynamics of Q1 and Q2 were examined by measuring

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Título según SCIELO: LOCATION, ORIENTATION AND DYNAMICS OF TWO MOLECULES WITH MITOCHONDRIAL ACTIVITY DISSOLVED IN ANIONIC LYOMESOPHASE: A �H-NMR AND MD STUDY
Título de la Revista: Journal of the Chilean Chemical Society
Volumen: 57
Número: 3
Editorial: SOC CHILENA QUIMICA
Fecha de publicación: 2012
Página de inicio: 1295
Página final: 1300
Idioma: en
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000300021&lng=en&nrm=iso&tlng=en
DOI:

10.4067/S0717-97072012000300021

Notas: SCIELO