Tiroglobulina y sus limitaciones en el seguimiento del carcinoma diferenciado del tiroides: Report of two cases

Velasco L, Soledad; Solar G, Antonieta; CRUZ O, FRANCISCO; Quintana F, Juan Carlos; León R, Augusto; Mosso G, Lorena; Fardella, Carlos

Keywords: thyroid neoplasms, thyroglobulin, carcinoma, papillary

Abstract

Thyroid carcinoma is the most prevalent endocrine tumor, and the papillary carcinoma (PC) is the most common histological type. In the follow-up, after thyroidectomy serum thyroglobulin (s-Tg) is used as a marker to evaluate recurrence of thyroid carcinoma. In most cases, this parameter allows an adequate diagnosis, but occasionally s-Tg may miss the detection of a recurrence. We report a 57 year-old female and a 36 year-old male sujected to a total thyroidectomy for a papillary thyroid carcinoma with intermediate and high-risk of recurrence. Both had a cervical recurrence without a concomitant increase in s-Tg levels. In both, Tg staining was positive in the tumor cells. These cases confirm that in these patients, the follow-up must be done with measurement of s-Tg and complementary diagnostic tests

Más información

Título según SCIELO: Tiroglobulina y sus limitaciones en el seguimiento del carcinoma diferenciado del tiroides: Report of two cases
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 135
Número: 4
Editorial: SOC MEDICA SANTIAGO
Fecha de publicación: 2007
Página de inicio: 506
Página final: 511
Idioma: es
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000400014&lng=en&nrm=iso&tlng=en
DOI:

10.4067/S0034-98872007000400014

Notas: SCIELO