IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY

Jullian, Carolina

Abstract

"The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydro xypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ratios and stability constants describing the extent of the formation of the complexes have been determined by phase-solubility measurements; in all cases type-A L diagrams have been obtained (soluble 1:1 complexes). The results showed that the complex efficiency of βCD and its derivatives was the order: DMβCD > HPβCD > βCD. The NMR study indicate that the inclusion of galangin in the cyclodextrin nano-cavity is different depending on the type of cyclodextrin used."

Más información

Título según SCOPUS: Improvement of galangin solubility using native and derivative cyclodextrins. An UV-Vis and NMR study
Título según SCIELO: IMPROVEMENT OF GALANGIN SOLUBILITY USING NATIVE AND DERIVATIVE CYCLODEXTRINS: AN UV-Vis AND NMR STUDY
Título de la Revista: Journal of the Chilean Chemical Society
Volumen: 54
Número: 2
Editorial: SOC CHILENA QUIMICA
Fecha de publicación: 2009
Página de inicio: 201
Página final: 203
Idioma: en
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072009000200025&lng=en&nrm=iso&tlng=en
DOI:

10.4067/S0717-97072009000200025

Notas: SCIELO, SCOPUS