Medullary thyroid cancer. Review of 28 patients

Pulgar D.; Jans, J; Petric, M; León, A; Camus, M; Goni, I; Dominguez F.; Droppelmann, N; Claure, R; GONZALEZ, H

Abstract

Background: Medullary thyroid cancer (MTC) represents approximately 5% of all thyroid cancers. Surgery is the only curative treatment, which includes total thyroidectomy and in most cases, neck dissection. Aim: To report our 10-year experience with surgical treatment of MTC. Material and Methods: Review of medical records and pathology reports of a university hospital. We retrieved data from 28 patients aged 47.2 +/- 16 years (21 women) operated for a MTC treated between June 2002 and June 2012. Results: In 20 patients, MTC was diagnosed in the preoperative period. Total thyroidectomy was performed in all cases and included a neck dissection in 24 patients. Median follow-up was 48 (2-120) months. Twenty-five patients (89.2%) achieved complete remission of the disease and three had disease recurrence. There were no deaths during the follow up. Conclusions: The diagnosis of MTC is mainly based on cytology. Total thyroidectomy with neck dissection is the treatment of choice. An early-stage diagnosis is associated with low rates of recurrence and absence of mortality.

Más información

Título según WOS: Medullary thyroid cancer. Review of 28 patients
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 141
Número: 11
Editorial: SOC MEDICA SANTIAGO
Fecha de publicación: 2013
Página de inicio: 1395
Página final: 1401
Idioma: Spanish
Notas: ISI