Subjects with Impaired Fasting Glucose: Evolution in a Period of 6 Years

Leiva E.; Mujica, V; Orrego R.; Wehinger, S; soto A.; Icaza G.; Vásquez M; Diaz L.; Andrews, M; Arredondo M.

Abstract

Aim. To study the evolution of impaired fasting glucose (IFG), considering glucose and HbA1c levels and risk factors associated, in a period of 6 years. Methods. We studied 94 subjects with impaired fasting glucose (IFG) that were diagnosed in 2005 and followed up to 2012. Glucose and HbA1c levels were determined. A descriptive analysis of contingence charts was performed in order to study the evolution in the development of type-2 diabetesmellitus (T2DM). Results. Twenty-eight of ninety-four subjects became T2DM; 51/94 remained with IFG; and 20/94 presented normal fasting glucose. From the 28 diabetic subjects, 9 had already developed diabetes and were under treatment with oral hypoglycemic agents; 5 were diagnosed with plasma glucose < 126mg/dL, but with HbA1c over 6.5%. In those who developed diabetes, 15/28 had a family history of T2DM in first relative degree. Also, diabetic subjects had a BMI significantly higher than nodiabetics (t test: P < 0.01). The individuals that in 2005 had the highest BMI are those who currently have diabetes. Conclusion. The IFG constitutes a condition of high risk of developing T2DM in a few years, especially over 110mg/dL and in obesity patients.

Más información

Título según WOS: Subjects with Impaired Fasting Glucose: Evolution in a Period of 6 Years
Título según SCOPUS: Subjects with impaired fasting glucose: Evolution in a period of 6 years
Título de la Revista: JOURNAL OF DIABETES RESEARCH
Volumen: 2014
Editorial: HINDAWI LTD
Fecha de publicación: 2014
Idioma: English
DOI:

10.1155/2014/710370

Notas: ISI, SCOPUS