High intensity interval training improves glycemic control and aerobic capacity in glucose intolerant patients

Mancilla R.; Torres P.; Alvarez C.; Schifferli, I; Sapunar, J; Diaz, E.

Abstract

Background: Proper exercise training modifies intra miocellular energy utilization, glucose transport and mitochondrial biogenesis. Aim: To determine the therapeutic effects of a high intensity intermittent training (HIIT) program on glucose homeostasis, physical fitness and body fat in glucose intolerant patients. Patients and Methods: Eighteen patients with overweight or obesity and glucose intolerance were invited to participate in an exercise program consisting in three sessions per week for 3 months. Ten participants aged 35 +/- 13 years who attended > 26 of the planned 36 sessions, were considered as adherent to exercise. The other eight participants aged 37 +/- 17 years, who attended to a mean of 13 sessions, were considered as non-adherent. Both groups had similar body weight, body mass index, body fat, plasma glucose 2 h after an oral glucose load and maximal oxygen uptake. All these variables were measured at the end of exercise intervention. Each session consisted of 1 min exercise of cycling at maximal intensity until muscle fatigue followed by 2 min rest, repeated 10 times. Results: Among adherent participants, twelve weeks of HIIT improved significantly maximal oxygen uptake (6.1 + 3.6 mL/kg/min or 24.6%), reduced 2 h post load blood glucose (-33.7 + 47.9 mg/dL or -12.5%) and body fat (-4.3 + 5.6 kg). No significant changes were observed in the non-adherent group. Conclusions: HIIT exercise reduces blood glucose after an oral load in glucose intolerant patients.

Más información

Título según WOS: High intensity interval training improves glycemic control and aerobic capacity in glucose intolerant patients
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 142
Número: 1
Editorial: SOC MEDICA SANTIAGO
Fecha de publicación: 2014
Página de inicio: 34
Página final: 39
Idioma: Spanish
Notas: ISI