New Diterpenes from Azorella spinosa

Astudillo, L; Gutiérrez M; Quesada, L; San Martin, A; Espinoza L.; Peñailillo P.

Abstract

Two new diterpenes,2-acetoxy-13-hydroxy-mulin-11-ene and 2-acetoxy-mulin-11, 13-diene,have been isolated from the aerial parts of Azorella spinosa and their structures determined by spectroscopic and conventional chemical methods. Furthermore, 2, 13-dihydroxy-mulin-11-ene was obtained using a basic hydrolysis of the first compound. Two diterpenes reported for other Azorella species have also been found, namely mulinolic acid and 13 beta-hydroxyazorellane, as well as the triterpene lactone of ursolic acid,quercetin, and 7-hydroxycoumarin. The compounds were evaluated using antibacterial, antioxidant and enzymatic assays; no significant activity was detected.

Más información

Título según WOS: New Diterpenes from Azorella spinosa
Título de la Revista: NATURAL PRODUCT COMMUNICATIONS
Volumen: 9
Número: 1
Editorial: SAGE PUBLICATIONS INC
Fecha de publicación: 2014
Página de inicio: 9
Página final: 12
Idioma: English
Notas: ISI