Efficient image reconstruction in fluorescence diffuse opitcal tomography (fDOT) using data and solution compression

Correia T.; Rudge, T.; Arridge, S

Keywords: fluorescence, wavelets, inverse problems, data compression

Abstract

Current fluorescence diffuse optical tomography (fDOT) systems can provide large data sets and, in addition, the unknown parameters to be estimated are so numerous that the sensitivity matrix is too large to store. Alternatively, iterative methods can be used, but they can be extremely slow at converging when dealing with large matrices. A few approaches suitable for the reconstruction of images from very large data sets have been developed. However, they either require explicit construction of the sensitivity matrix, suffer from slow computation times or can only be applied to restricted geometries. We introduce a method for fast reconstruction in fDOT with large data and solution spaces, which preserves the resolution of the forward operator whilst compressing its representation. The method does not require construction of the full matrix, and thus, allows storage and direct inversion of the explicitly constructed compressed system matrix. The method is tested using simulated data. Results show that the fDOT image reconstruction problem can be effectively compressed, without siginificant loss of information and with the added advantage of reducing image noise.

Más información

Título según WOS: Efficient image reconstruction in fluorescence diffuse opitcal tomography (fDOT) using data and solution compression
Título de la Revista: COMPUTATIONAL OPTICS 2024
Volumen: 8799
Editorial: SPIE-INT SOC OPTICAL ENGINEERING
Fecha de publicación: 2013
Idioma: English
DOI:

10.1117/12.2032548

Notas: ISI