Searching for Common Pathogenic Pathways leading to Neuronal and Hepatic Damage in Niemann-Pick Diseases
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Fecha de publicación: | 2015 |
Objetivos: | General Goal: To identify novel potential therapeutic targets for intervention in NPDs establishing whether c-Abl signaling pathways involving p73, HDAC2 and autophagy in the cerebellum and impaired NLRP3 inflammasome and cathepsins B and D in the liver are part of the common pathogenic mechanisms. |
Año de Inicio/Término: | 2015-2019 |
Financiamiento/Sponsor: | CONICYT |
Rol del Usuario: | INVESTIGADOR(A) RESPONSABLE |
DOI: |
1150186 |