H-1 and C-13 NMR spectral characterization of some antimalarial in vitro 2,4-diamino-10-methylpyrimido[4,5-b]-5-quinolone derivatives
Abstract
We report the H-1 NMR and C-13 NMR chemical shifts and J(H,H), J(H,F) and J(C,F) coupling constants of 13 2,4-diamino-10-methylpyrimido[4,5-b]-5-quinolone derivatives, some of them with moderate activity against Plasmodium falciparum in vitro. They were characterized and assigned on the basis of H-1, C-13 and C-13-H-1 (short- and long-range) correlated spectra. Copyright (C) 2002 John Wiley Sons, Ltd.
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Título según WOS: | ID WOS:000176373300011 Not found in local WOS DB |
Título de la Revista: | MAGNETIC RESONANCE IN CHEMISTRY |
Volumen: | 40 |
Número: | 7 |
Editorial: | WILEY-BLACKWELL |
Fecha de publicación: | 2002 |
Página de inicio: | 477 |
Página final: | 479 |
DOI: |
10.1002/mrc.1024 |
Notas: | ISI |