H-1 and C-13 NMR spectral characterization of some antimalarial in vitro 2,4-diamino-10-methylpyrimido[4,5-b]-5-quinolone derivatives

Charris, JE; Dominguez, JN; Gamboa, N; Angel, J; Pina, N; Guerra, M; Michelena, E; Lopez, SE

Abstract

We report the H-1 NMR and C-13 NMR chemical shifts and J(H,H), J(H,F) and J(C,F) coupling constants of 13 2,4-diamino-10-methylpyrimido[4,5-b]-5-quinolone derivatives, some of them with moderate activity against Plasmodium falciparum in vitro. They were characterized and assigned on the basis of H-1, C-13 and C-13-H-1 (short- and long-range) correlated spectra. Copyright (C) 2002 John Wiley Sons, Ltd.

Más información

Título según WOS: ID WOS:000176373300011 Not found in local WOS DB
Título de la Revista: MAGNETIC RESONANCE IN CHEMISTRY
Volumen: 40
Número: 7
Editorial: WILEY-BLACKWELL
Fecha de publicación: 2002
Página de inicio: 477
Página final: 479
DOI:

10.1002/mrc.1024

Notas: ISI