Antiplatelet Activity of Natural Bioactive Extracts from Mango (Mangifera Indica L.) and its By-Products

Elena Alanon, Maria; Palomo, Ivan; Rodriguez, Lyanne; FUENTES, EDUARDO; Arraez-Roman, David; Segura-Carretero, Antonio

Abstract

The potential antiplatelet aggregation effects of mango pulp and its by-products (peel, husk seed, and seed) due to the presence of bioactive compounds were explored. Among them, mango seed exhibited a 72% percentage inhibition of platelet aggregation induced by adenosine 5'-diphosphate (ADP) agonist with a demonstrated dose-dependent effect. This biological feature could be caused by the chemical differences in phenolic composition. Mango seed was especially rich in monogalloyl compounds, tetra- and penta-galloylglucose, ellagic acid, mangiferin, and benzophenones such as maclurin derivatives and iriflophenone glucoside. Mangiferin showed an inhibitory effect of 31%, suggesting its key role as one of the main contributors to the antiplatelet activity of mango seed. Therefore, mango seed could be postulated as a natural source of bioactive compounds with antiplatelet properties to design functional foods or complementary therapeutic treatments.

Más información

Título según WOS: Antiplatelet Activity of Natural Bioactive Extracts from Mango (Mangifera Indica L.) and its By-Products
Título según SCOPUS: Antiplatelet activity of natural bioactive extracts from mango (Mangifera indica l.) and its by-products
Título de la Revista: ANTIOXIDANTS
Volumen: 8
Número: 11
Editorial: MDPI
Fecha de publicación: 2019
Idioma: English
DOI:

10.3390/antiox8110517

Notas: ISI, SCOPUS