Chemical hypoxia induces pro-inflammatory signals in fat-laden hepatocytes and contributes to cellular crosstalk with Kupffer cells through extracellular vesicles

Hernández A.; Geng Y.; Sepúlveda R.; Solís N.; Torres J.; Arab J.P.; Barrera F.; Cabrera D.; Moshage H.; Arrese M.

Abstract

Background: Obstructive sleep apnea syndrome (OSAS) is associated to intermittent hypoxia (IH) and is an aggravating factor of non-alcoholic fatty liver disease (NAFLD). We investigated the effects of hypoxia in both in vitro and in vivo models of NAFLD.

Más información

Título según WOS: Chemical hypoxia induces pro-inflammatory signals in fat-laden hepatocytes and contributes to cellular crosstalk with Kupffer cells through extracellular vesicles
Título según SCOPUS: Chemical hypoxia induces pro-inflammatory signals in fat-laden hepatocytes and contributes to cellular crosstalk with Kupffer cells through extracellular vesicles
Título de la Revista: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Volumen: 1866
Número: 6
Editorial: Elsevier
Fecha de publicación: 2020
Idioma: English
DOI:

10.1016/J.BBADIS.2020.165753

Notas: ISI, SCOPUS