Article ISI SCOPUS
SYNTHETIC COMMUNICATIONS  (2004)

Synthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action

Pessoa-Mahana H.; Gajardo, GR; Araya-Maturana, R; Carcamo, JK; Pessoa-Mahana, CD

Abstract

We report here the synthesis of substituted 4-chloro-N-[3-oxo-3-(4-aryl-1- piperazinyl)-propyl] benzamides (5-9), as potential new antidepressants, incorporating in a single molecule structural moieties related to a dual pharmacological profile: MAO-A inhibitor and 5-HT1A receptor affinity.

Más información

Título según WOS: Synthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action
Título según SCOPUS: Synthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action
Título de la Revista: SYNTHETIC COMMUNICATIONS
Volumen: 34
Número: 14
Editorial: TAYLOR & FRANCIS INC
Fecha de publicación: 2004
Página de inicio: 2513
Página final: 2521
Idioma: English
DOI:

10.1080/SCC-200025581
Notas: ISI, SCOPUS