Chromatin from two classes of platyhelminthes display both protist H1 and higher eukaryote core histones

Galindo, M; Varela, N; Espinoza, I; Toro, GC; Hellman, U; Wernstedt, C; Galanti N.

Abstract

Histones from the parasitic platyhelminthes, Echinococcus granulosus and Fasciola hepatica, were systematically characterized. Core histones H2A, H2B, H3 and H4, which were identified on the basis of amino acid sequencing and mass spectrometry data, showed conserved electrophoretic patterns. Histones H1, identified on the basis of physicochemical properties, amino acid composition and amino acid sequencing, showed divergence, both in their number and electrophoretic mobilities, between the two species and among other organisms. According to these data, core histones but not H1 histones, would be stabilized during evolution at the level of platyhelminthes. © 2004 Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies.

Más información

Título según WOS: Chromatin from two classes of platyhelminthes display both protist H1 and higher eukaryote core histones
Título según SCOPUS: Chromatin from two classes of platyhelminthes display both protist H1 and higher eukaryote core histones
Título de la Revista: FEBS LETTERS
Volumen: 567
Número: 02-mar
Editorial: Wiley
Fecha de publicación: 2004
Página de inicio: 225
Página final: 229
Idioma: English
URL: http://linkinghub.elsevier.com/retrieve/pii/S0014579304005423
DOI:

10.1016/j.febslet.2004.04.065

Notas: ISI, SCOPUS