REGIOSELECTIVE MUCOR-MIEHEI LIPASE-CATALYZED SYNTHESIS OF PODANDS CONTAINING A 1,3-BIS(1H-PYRAZOL-1-YL)PROPANE UNIT
Abstract
The synthesis of podands (acyclic crown ethers) including a 1,3-bis(1H-pyrazol-1-yl)propane unit in their molecule is described. The key step of this synthesis was a regoioselective lipase-catalyzed transesterification of the dipyrazolic tetraethylester 1 with monomethylether polyethyleneglycols. The ionophoric properties of the podands 4a-d as carriers of cations were evaluated. Molecular modelling studies and quantum-chemical calculations were used in order to elucidate the superestructures of the complexes with ammonium cations.
Más información
Título según WOS: | ID WOS:A1995QK04900022 Not found in local WOS DB |
Título de la Revista: | TETRAHEDRON |
Volumen: | 51 |
Número: | 8 |
Editorial: | PERGAMON-ELSEVIER SCIENCE LTD |
Fecha de publicación: | 1995 |
Página de inicio: | 2417 |
Página final: | 2426 |
DOI: |
10.1016/0040-4020(94)01106-A |
Notas: | ISI |