REGIOSELECTIVE MUCOR-MIEHEI LIPASE-CATALYZED SYNTHESIS OF PODANDS CONTAINING A 1,3-BIS(1H-PYRAZOL-1-YL)PROPANE UNIT

FIERROS, M; CONDE, S; MARTINEZ, A; NAVARRO, P; RODRIGUEZFRANCO, MI

Abstract

The synthesis of podands (acyclic crown ethers) including a 1,3-bis(1H-pyrazol-1-yl)propane unit in their molecule is described. The key step of this synthesis was a regoioselective lipase-catalyzed transesterification of the dipyrazolic tetraethylester 1 with monomethylether polyethyleneglycols. The ionophoric properties of the podands 4a-d as carriers of cations were evaluated. Molecular modelling studies and quantum-chemical calculations were used in order to elucidate the superestructures of the complexes with ammonium cations.

Más información

Título según WOS: ID WOS:A1995QK04900022 Not found in local WOS DB
Título de la Revista: TETRAHEDRON
Volumen: 51
Número: 8
Editorial: PERGAMON-ELSEVIER SCIENCE LTD
Fecha de publicación: 1995
Página de inicio: 2417
Página final: 2426
DOI:

10.1016/0040-4020(94)01106-A

Notas: ISI