Chlorophenylmethyl benzothiadiazine dioxides derivatives: Potent human cytomegalovirus inhibitors
Abstract
Modifications of our previously reported lead compounds, acyclonucleosides derived from 2,1,3-benzothiadiazine dioxides, in the search for inhibitors of human cytomegalovirus (HCMV), lead us to identify the chlorophenylmethyl benzothiadiazine dioxides derivatives as potent HCMV inhibitors. The synthesis and antiviral data of this second-generation of benzothiadiazine dioxide compounds are reported. (C) 1999 Elsevier Science Ltd. All rights reserved.
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Título según WOS: | ID WOS:000083562300014 Not found in local WOS DB |
Título de la Revista: | BIOORGANIC MEDICINAL CHEMISTRY LETTERS |
Volumen: | 9 |
Número: | 21 |
Editorial: | PERGAMON-ELSEVIER SCIENCE LTD |
Fecha de publicación: | 1999 |
Página de inicio: | 3133 |
Página final: | 3136 |
DOI: |
10.1016/S0960-894X(99)00538-7 |
Notas: | ISI |