PRODUCTION OF REFERENCE MATERIAL FOR THE DETECTION AND QUANTIFICATION OF DINOPHYSISTONIN-3 TOXIN, A DERIVATIVE OF DINOPHYSISTONIN-1, THE MOST POTENT DIARRHETIC TOXIN. PURIFICATION FROM CONTAMINATED SHELLFISH.

GarcÍa, Carlos Enrique; Lagos, N.A.

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Fecha de publicación: 2009
Objetivos: To identify, quantitate and purify Dinophysistoxin-3 (DTX-3, 7-O-acyl-Dinophysistoxin-1) starting from contaminated mollusks (1 to 2 tons) as raw material and to develop a routinary biochemical purification procedure for this toxin.
Instrumento: FONDECYT
Año de Inicio/Término: 2009-2012
Financiamiento/Sponsor: CONICYT
Rol del Usuario: INVESTIGADOR(A) RESPONSABLE
URL: http://repositorio.conicyt.cl/handle/10533/120697
DOI:

1090058

Notas: Diarrheic Shellfish Poison (DSP) is associated to the most widely distributed marine toxin related syndrome across the world. It was described in Japan, after a 1976 massive intoxication caused by ingestion of DSP contaminated mollusks. Main symptoms of this syndrome are: diarrhea, nausea (80%)