A novel, accurate and robust three-dimensional quantification of circulation using finite- element methods in 4D Flow MRI data of thoracic aorta

Julio Sotelo, Malenka M Bissell, Yaxin Jiang, Hernan Mella, Joaquin Mura, Sergio Uribe

Abstract

The circulation is normally analyzed in a 2D cross-section of the aorta, manually placed. To avoid this problem, evaluate and validate a new methodology based on Finite Elements (FE) to calculate the circulation in three-dimensions, in in-silico models, and in the ascending aorta of a group of volunteers and patients. In in-silico experiment, we obtain an RMSE of the circulation values less than 1.6e-6. We also found that significant differences exist between volunteers and patients with a p-value of 0.0283. Our method is straight forward to calculate, accurate and robust throughout different resolutions and noise levels.

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Fecha de publicación: 2020
URL: https://www.researchgate.net/publication/343862523_A_novel_accurate_and_robust_three-dimensional_quantification_of_circulation_using_finite-_element_methods_in_4D_Flow_MRI_data_of_thoracic_aorta