Transcriptional and Functional Analysis of CD1c(+) Human Dendritic Cells Identifies a CD163(+) Subset Priming CD8(+)CD103(+) T Cells
Abstract
Bourdely et al. identify human CD88âCD1c+CD163+ DC3s as a pro-inflammatory phagocyte lineage sharing features with monocytes and conventional DCs. DC3s efficiently induce differentiation of CD103+CD8+ T cells in vitro, and their infiltration correlates with CD8+CD69+CD103+ TRM accumulation in breast tumors.
Más información
| Título según WOS: | Transcriptional and Functional Analysis of CD1c(+) Human Dendritic Cells Identifies a CD163(+) Subset Priming CD8(+)CD103(+) T Cells |
| Título según SCOPUS: | Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells |
| Título de la Revista: | Immunity |
| Volumen: | 53 |
| Número: | 2 |
| Editorial: | Cell Press |
| Fecha de publicación: | 2020 |
| Página final: | 352.e8 |
| Idioma: | English |
| DOI: |
10.1016/j.immuni.2020.06.002 |
| Notas: | ISI, SCOPUS |