4-(3-Methoxyphenyl)-5-(2-thienylmethyl)-2,4-dihydro-3H-1,2,4-triazole-3-selone: Synthesis, structural characteristics and reactions

Osmanov, Vladimir K.; Askerov, Rizvan K.; Chipinsky, Evgeniy, V; Borisova, Galina N.; Khrustalev, Victor N.; Chizhov, Alexander O.; Peregudov, Alexander S.; Cisterna, Jonathan; Borisov, Alexander, V; Brito, Ivan

Abstract

The title compound 4-(3-methoxypheny1)-3-(2-thienylmethyl)-4,5-dihydro-3H-1,2,4-triazole-3-selone 2 was synthesized by two-step procedure including condensation of 1-isoselenocyanato-3-methoxybenzene with 2-(2-thienyl)acetohydrazide to selenosemicarbazide 1 and its intramolecular cyclization. Oxidation of selone 2 by atmospheric oxygen or hydrogen peroxide furnished corresponding diselenide 3 or product of elimination of selenium 1,2,4-triazole 4. Alkylation of compound 2 by benzyl chloride leads to the formation of selenide 5. The synthesized compounds have been characterized by spectroscopic techniques and the structures of 3,4 and 5 were confirmed by X-ray diffraction techniques and the supramolecular contacts were analyzed by Hirshfeld surface analyses. (C) 2020 Elsevier B.V. All rights reserved.

Más información

Título según WOS: 4-(3-Methoxyphenyl)-5-(2-thienylmethyl)-2,4-dihydro-3H-1,2,4-triazole-3-selone: Synthesis, structural characteristics and reactions
Título de la Revista: JOURNAL OF MOLECULAR STRUCTURE
Volumen: 1227
Editorial: ELSEVIER SCIENCE BV
Fecha de publicación: 2021
DOI:

10.1016/j.molstruc.2020.129537

Notas: ISI