Hemolytic uremic syndrome associated with Entamoeba histolytica intestinal infection

Cavagnaro F.; Guzmán C; Harris P.

Abstract

Amebiasis secondary to Entamoeba histolytica (E. histolytica) continues to be a major source of morbidity and mortality worldwide, mainly in developing countries. An association between amebic dysentery and hemolytic uremic syndrome (HUS) has been mentioned, but a cause-and-effect relationship has never been confirmed. We report the case of an 11-year-old healthy white female who developed severe bloody diarrhea after drinking contaminated unboiled water, developing classic HUS and requiring acute intermittent hemodialysis. The etiological study confirmed numerous cysts and hematophagous trophozoites of E. histolytica on stool smear, but without evidence of other pathogens. This report contributes to the concept that classic post-diarrheal HUS, usually related to colitis secondary to enterohemorragic Shiga-toxin producing Escherichia coli (E.coli) strains, may be associated with other pathogens, including E. histolytica. Additional information regarding mechanisms of virulence of E. histolytica and host immunological reaction is needed to clarify the temporal association of these two disorders (HUS and amebiasis). © IPNA 2005.

Más información

Título según WOS: Hemolytic uremic syndrome associated with Entamoeba histolytica intestinal infection
Título según SCOPUS: Hemolytic uremic syndrome associated with Entamoeba histolytica intestinal infection
Título de la Revista: PEDIATRIC NEPHROLOGY
Volumen: 21
Número: 1
Editorial: Springer
Fecha de publicación: 2006
Página de inicio: 126
Página final: 128
Idioma: English
URL: http://link.springer.com/10.1007/s00467-005-2069-4
DOI:

10.1007/s00467-005-2069-4

Notas: ISI, SCOPUS