Abstract

D-glucose acts as an energy source in living organisms. Also, it plays a major role in metabolic homeostasis. The investigation of metal oxides as electrochemical sensors for glucose has gained considerable attention. This is because of their redox behavior, high stability, low cost compared to noble metals, high sensitivity, and rapid response to analytes. The glucose sensing performance of conducting polymers and carbon materials can be significantly enhanced by the functionalization of a suitable moiety. The shortcomings of pure metallic electrodes as glucose sensors can be overcome by making alloy nanostructures. Nanocomposites have wide interest in many fields, including glucose sensors. Based on the necessity of glucose determination, researchers have developed many quantification methods. Among those methods, the electrochemical method has attention worldwide due to its simplicity, sensitivity, portability, and cost effectiveness. The fabrication of nanocomposites by using various metals and/or metal compounds, conducting polymers, and carbon materials has been explored for their promising electrochemical glucose sensing properties.