Portal del Investigador
ROLE OF ACE2 AND ANGIOTENSIN-(1-9) IN THE DEVELOPMENTOF HEART FAILURE WITH PRESERVED EJECTION FRACTION INMICE
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| Fecha de publicación: | 2022 |
| Objetivos: | Aim 1: To assess the ACE/Ang II and ACE2/Ang-(1–9) axes in an experimental HFpEF mouse model (high-fat diet plus L-NAME) throughout the progression of HFpEF. |
| Instrumento: | FONDECYT |
| Año de Inicio/Término: | 2022-2025 |
| Financiamiento/Sponsor: | CONICYT |
| Rol del Usuario: | INVESTIGADOR(A) RESPONSABLE |
| DOI: |
1221585 |
| Notas: | Aim 2: To determine macrophage phenotype in cardiac tissue in an experimental HFpEF mouse model (high-fat diet plus L-NAME) throughout the progression of HFpEF. Aim 3: To study the participation of ACE2 and Ang-(1–9) in cardiac macrophage phenotype and myocardial remodeling and function throughout t |