Portal del Investigador
Role of KDELR signaling pathway in cancer cell metabolism: integrating the secretory pathway with lipid droplet and mitochondrial function.
Más información
| Fecha de publicación: | 2022 |
| Objetivos: | To demonstrate if TIDeRS pathway: 1) stimulates lipophagy in tumor cell models. 2) stimulates FA transfer to mitochondria in tumor cell models. 3) sustain Metalloproteinase’s secretion in tumor cell models, and 4) enhance lipophagy and FA transfer to mitochondria in tumor aggressiveness. |
| Instrumento: | FONDECYT |
| Año de Inicio/Término: | 2022-2026 |
| Financiamiento/Sponsor: | CONICYT |
| Rol del Usuario: | INVESTIGADOR(A) RESPONSABLE |
| DOI: |
1221374 |
| Notas: | The Novelty and potential impact of this proposal is to provide novel insights about the contribution of TIDeRS pathway in LD metabolism by regulating and functional organelles engagement that modulate autophagy and lipophagy with an impact on tumor aggressiveness. |