Potential Joint Effect of the SNP rs3749474T and SNP rs4864548AAlleles of the CLOCK Gene on Nutritional Status and Chronotype in Young University Students

Pino Astorga, Carolina; Valladares Vega, Macarena

Abstract

Objective: To compare the nutritional status, chronotype and eating behavior of a subject who simultaneously has the rs3749474T and rs4864548A polymorphisms to groups of subjects who have only one of these polymorphisms. Methods: The presence of the polymorphisms was established by PCR. BMI, cardiovascular risk, and fat percentage were determined as described by Durnin and Womersley and the Siri equation. The TFEQ-P19 questionnaire (adapted to the Chilean population) and the Hor-ne-Ostberg questionnaire were applied. Results: The subject with both polymorphisms presented obesity, cardiovascular risk, and late-night chronotype. Its scores on the dimensions of uncontrolled feeding and emotional feeding were low, and its score for cognitive restriction was the highest. Conclusions: The presence of the TA haplotype (rs3749474; rs4864548A) would increase the possibility of having a late-night type chronotype, risk of obesity, and cardiovascular risk associated with waist centimeters.

Más información

Título según WOS: ID SCIELO:S0120-55522021000100011 Not found in local WOS DB
Título según SCOPUS: Potential joint effect of the snp rs3749474t and snp rs4864548aalleles of the clock gene on nutritional status and chronotype in young university students
Título de la Revista: Salud Uninorte
Volumen: 37
Número: 1
Editorial: Universidad del Norte
Fecha de publicación: 2021
Página de inicio: 606
Página final: 618
Idioma: Spanish
DOI:

10.14482/sun.37.1.613.2

Notas: ISI, SCOPUS