New trisubstituted purine derivatives as potent inhibitors and PROTAC warheads against mutated Bcr-Abl and Btk: A combined strategy to target key proteins for the treatment of leukaemia
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| Fecha de publicación: | 2023 |
| Objetivos: | This research is focused on the development and optimisation of novel purine derivatives targeting two kinases involved in leukaemia, from design, in vitro biological study to in vivo assays. |
| Instrumento: | FONDECYT |
| Año de Inicio/Término: | 2023-2026 |
| Financiamiento/Sponsor: | CONICYT |
| Rol del Usuario: | COINVESTIGADOR(A) |
| DOI: |
1231199 |