Enantioselective total syntheses of ropivacaine and its analogues

Shankaraiah, N.; Pilli, RA; Santos, LS

Abstract

An alternative asymmetric synthesis of ropivacaine and analogues employing the 'cation pool' strategy and host/guest supramolecular co-catalysis approach is presented. In this study, chiral auxiliaries, several soft nucleophiles as well as one-pot conditions for anodic oxidation, followed by nucleophilic addition, have been applied. © 2008 Elsevier Ltd. All rights reserved.

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Título según WOS: Enantioselective total syntheses of ropivacaine and its analogues
Título según SCOPUS: Enantioselective total syntheses of ropivacaine and its analogues
Título de la Revista: TETRAHEDRON LETTERS
Volumen: 49
Número: 34
Editorial: PERGAMON-ELSEVIER SCIENCE LTD
Fecha de publicación: 2008
Página de inicio: 5098
Página final: 5100
Idioma: English
URL: http://linkinghub.elsevier.com/retrieve/pii/S0040403908011222
DOI:

10.1016/j.tetlet.2008.06.028

Notas: ISI, SCOPUS