Capturing the non-stationarity of whole-brain dynamics underlying human brain states

Galadi, J. A.; Pereira, S. Silva; Perl, Y. Sanz; Kringelbach, M. L.; Gayte, I.; Laufs, H.; Tagliazucchi, E.; Langa, J. A.; Deco, G.

Abstract

Brain dynamics depicts an extremely complex energy landscape that changes over time, and its characterisation is a central unsolved problem in neuroscience. We approximate the non-stationary landscape sustained by the human brain through a novel mathematical formalism that allows us characterise the attractor structure, i.e. the stationary points and their connections. Due to its time-varying nature, the structure of the global attractor and the corresponding number of energy levels changes over time. We apply this formalism to distinguish quantitatively between the different human brain states of wakefulness and different stages of sleep, as a step towards future clinical applications.

Más información

Título según WOS: ID WOS:000696967000001 Not found in local WOS DB
Título de la Revista: NEUROIMAGE
Volumen: 244
Editorial: ACADEMIC PRESS INC ELSEVIER SCIENCE
Fecha de publicación: 2021
DOI:

10.1016/j.neuroimage.2021.118551

Notas: ISI