Genetic variants associated with longitudinal changes in brain structure across the lifespan

Brouwer, Rachel M.; Klein, Marieke; Grasby, Katrina L.; Schnack, Hugo G.; Jahanshad, Neda; Teeuw, Jalmar; Thomopoulos, Sophia I.; Sprooten, Emma; Gogtay, Nitin; Panizzon, Matthew S.; Olde Loohuis, Loes M.; Whelan, Christopher D.; Aghajani, Moji; Alloza, Clara; Alanaes, Dag; et. al.

Abstract

Human brain structure changes throughout the lifespan. Brouwer et al. identified genetic variants that affect rates of brain growth and atrophy. The genes are linked to early brain development and neurodegeneration and suggest involvement of metabolic processes.

Más información

Título según WOS: Genetic variants associated with longitudinal changes in brain structure across the lifespan
Título de la Revista: NATURE NEUROSCIENCE
Volumen: 25
Número: 4
Editorial: NATURE PORTFOLIO
Fecha de publicación: 2022
Página de inicio: 421
Página final: 432
DOI:

10.1038/S41593-022-01042-4

Notas: ISI