MAGNETIC BEHAVIOR AND ANTIBACTERIAL ACTIVITY OF IRON (III) COMPLEXES

Cortes-Cortes, P; Atria, AM; Contreras M.; Peña O.; Fernández K.; Corsini, G

Abstract

"The preparation, magnetic characterization and antimicrobial properties of the complexes [Fe(3)0(CH3COO)6(CH3COOH)(H(2)0)]Cl(MeImid)-(H(2)0) (1) and [Fe(4)0(2)(CH3COO)(7)0(2)(BPA)2(H(2)0)]- CH.25(CH3CH2OH)(H(2)0) (2), where Melmid is 2-methyl-imidazolium and BPA is 2,2'-bipyridine, are described. The variable temperature susceptibilities of these complexes were investigated in the temperature range 2-300K. The data have been modeled on the assumption of ""butterfly"" arranged for (2) and equilateral triangle of ferric ions for (1). The antimicrobial activities of these complexes have been screened in vitro against different bacterial strains. The complexes (1) and (2) display activity over Gram negative bacteria and these compounds not present activity over Gram positive strains. These complexes have bacteriostatic effect over bacterial target. The toxicity analyses of iron complexes showed these have cytotoxicity effect to values around the MIC on human cell."

Más información

Título según WOS: Magnetic behavior and antibacterial activity of iron (III) complexes
Título según SCOPUS: Magnetic behavior and antibacterial activity of iron (III) complexes
Título según SCIELO: MAGNETIC BEHAVIOR AND ANTIBACTERIAL ACTIVITY OF IRON (III) COMPLEXES
Título de la Revista: Journal of the Chilean Chemical Society
Volumen: 53
Número: 2
Editorial: SOC CHILENA QUIMICA
Fecha de publicación: 2008
Página de inicio: 1527
Página final: 1532
Idioma: English
DOI:

10.4067/S0717-97072008000200019

Notas: ISI, SCIELO, SCOPUS