Three-stage sequential supercritical extraction in fixed bed extractor to obtain bioactive compounds from Leptocarpha rivularis leaves
Abstract
This work studied sequential supercritical extraction to obtain extracts from L. rivularis leaves. Extraction assays were carried out in three stages at 40 or 70?, with stage 1: 20 MPa with CO2, stage 2: 40 MPa with CO2, and stage 3: 40 MPa with ethanol-modified CO2 (5% wt.). The total extraction yield was higher at 70 ? (41.77 g/kg d.s.) than at 40?(32.57 g/kg d.s.). The total content of terpenes and flavonoids and the ability of the extracts to inhibit the a-amylase and a-glucosidase enzymes were measured. At 40 C the stage 1 extract had a greater inhibition effect on a-glucosidase and the stage 2 extract a greater inhibition effect on a-amylase. Sequential supercritical extraction was properly modeled using a diffusion model based on Fick's second law, and an effective diffusion coefficient was determined for each stage. Sequential supercritical extraction can be a method to increase the extraction of bioactive compounds.
Más información
Título según WOS: | ID WOS:000995584200001 Not found in local WOS DB |
Título de la Revista: | JOURNAL OF APPLIED RESEARCH ON MEDICINAL AND AROMATIC PLANTS |
Volumen: | 34 |
Editorial: | Elsevier |
Fecha de publicación: | 2023 |
DOI: |
10.1016/j.jarmap.2023.100460 |
Notas: | ISI |