Abstract

Objective: The aim of this study was to determine the effectiveness of dietary supplements to potentiate lean mass gain in hypertrophy during resistance training. Methods: A systematic review of primary quantitative data was performed to identify the relationship between the consumption of dietary supplements, lean mass gain, hypertrophy, and resistance training in humans with a body mass index between 18 and 30 kg/m2 were realized. The protocol was registered on PROSPERO. Results: Dietary supplementation with rice protein, Whey Protein, Graded Whey Protein, or beta-Hydroxy-beta-Methyl-Butyrate Free-Acid, along with resistance training seemed to increase lean body mass and body mass. In addition, a higher upper- and lower-body muscle strength were also found with resistance training and supplementation, while a decreased fat mass has been found after resistance training. Conclusion: Our results suggest that supplementation could be effective in resistance-trained subjects with a body mass index between 20 and 30 kg/m2 to improve body composition, potentiate lean body mass, muscle strength, and decrease total fat mass and percent of fat mass during resistance training.