Abstract

Purpose: 1) To characterize the glucose and blood pressure control in HLS adult participants based on four body composition phenotypes models from the Chilean National Health Survey 2016-17. 2) to associate the HLS and body composition phenotypes (based on calf and waist circumference [WC]) with arterial hypertension and diabetes markers. Method: A quantitative cross-sectional study based on the Chilean National Health Survey 2016-17, reporting adults with/without HLS based on four different phenotypes was carried out by the epidemiological group of the Institute of Rehabilitation and Exercise Sciences of the Universidad Andres bello, Chile (ICER-UNAB). Groups were as follows; Low skeletal muscle [SMM] and high waist circumference [WC] (Lsmm−Hwc, n=278), Low SMM and low WC (Lsmm−Lwc, n=479), High SMM and high WC (Hsmm−Hwc, n=2140), and High SMM and low WC (Hsmm−Lwc, n=2709). The primary outcomes were fasting plasma glucose, systolic, and diastolic blood pressure. Findings: In systolic blood pressure, there were significant differences between each Lsmm−Hwc (150 vs. 123 mmHg), Lsmm−Lwc (140 vs. 123 mmHg), and Hsmm−Hwc vs. the Reference group (145 vs. 123 mmHg, all P<0.0001). Systolic blood pressure reported significant Group x HLS interaction F (3.33), P=0.019, ES 0.004. In diastolic blood pressure, there were significant differences between each Lsmm−Hwc (74 vs. 72 mmHg) and Hsmm−Hwc vs. the Reference group (76 vs. 72 mmHg, both P<0.0001). Diastolic blood pressure reported significant Group x HLS interaction F (4.49), P=0.004, ES 0.005. Chilean adults with HLS, low SMM and high waist circumference shows a higher systolic and diastolic blood pressure.