Controlling neurotoxicity of reactive astrocytes in inflammatory conditions by altering endo-lysosomal trafficking
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Fecha de publicación: | 2024 |
Objetivos: | 1) whether Rab7 downregulation promotes aVb3 integrin recycling to the plasma membrane and whether it involves reduced endo-lysosomal trafficking; 2) the effects of Rab7 downregulation/overexpression on astrocyte reactivity and neuronal damage in vitro; and 3) the effects of Rab7 in vivo and astrocy |
Instrumento: | Fondecyt Regular |
Año de Inicio/Término: | 2024-2026 |
Financiamiento/Sponsor: | CONICYT |
Rol del Usuario: | INVESTIGADOR(A) RESPONSABLE |
DOI: |
FONDECYT Regular Chile Project Nº1240888 |