Solvent-Free Microwave-Assisted Synthesis of New 2-Aryl-Tetrahydroquinolines Using Three-Component Povarov Reaction

Astudillo, LS; Gutiérrez M; Gaete, H; Kouznetsov, VV; Melendez, CM; Palenzuela, JA; Vallejos G.

Abstract

A new series of 2-aryl-1, 2, 3, 4-tetrahydroquinolines has been synthesized in good yields through a BiCl 3-catalyzed three-component Povarov reaction (imino Diels-Alder cycloaddition) between anilines, benzaldehydes and Nvinylpyrrolidin-2-one in MeCN. The same series has been prepared without solvent using microwave radiation, which resulted in better yields, a considerable decrease in reaction times and simplified workup. ©2009.Bentham Science Publishers Ltd.

Más información

Título según WOS: Solvent-Free Microwave-Assisted Synthesis of New 2-Aryl-Tetrahydroquinolines Using Three-Component Povarov Reaction
Título según SCOPUS: Solvent-free microwave-assisted synthesis of new 2-Aryl- Tetrahydroquinolines using three-component povarov reaction
Título de la Revista: Letters in Organic Chemistry
Volumen: 6
Número: 3
Editorial: Bentham
Fecha de publicación: 2009
Página de inicio: 208
Página final: 212
Idioma: English
Notas: ISI, SCOPUS