GALLBLADDER POLYPS: CORRELATION AND AGREEMENT BETWEEN ULTRASONOGRAPHIC AND HISTOPATHOLOGICAL FINDINGS IN A POPULATION WITH HIGH INCIDENCE OF GALLBLADDER CANCER

Inzunza, Martin; Irarrazaval, Maria Jesus; Pozo, Paloma; Pimentel, Fernando; Crovari, Fernando; Ibanez, Luis

Abstract

Gallbladder polyps are becoming a common finding in ultrasound. The management has to consider th ptential risk of malignant lesions. AIMS: The aim of this study was to analyze he ultrasound findings in patients undergoing cholecystectmy due to glbladder polyps and compare them for histopthological findings (HPs). METHODS: Patients with an ultrsonogrphic diagnosis of gallbldder polyp and who underwent cholecystectomy from 2007 to 2020 were included in the study. RESULTS: A total of 447 patients were included, of whom 58% were women. The mean age was 45±12 years. The mean size f olyps in US was 7.9 ±3.6 mm. Notably, 9% of polyps were greatr than 10 mm, and single polyps were ignificantly larger than the multiple nes (p=0.003). Histopathological findings confirmed the resence of plyps in 88.4%, with a mean size of 4.8±3.4 mm. In all, 16 cases wee neoplastic polyps (4.1%), 4 of them being mlignancies, and ll wre single and larger thn 10 mm. We found a signifiant correlation between ultrasound and histopathological findings polyp size determination (r=0.44; p<0.001). The Bland-Altman analysis obtained an overestimation of the US size of 3.26 mm. The receiver operating characteristic (ROC) curve anlysis betwee both measures obtained an ea under the rcive operati g charcteristic curve (AUC) of 0.77 (95%CI 0.74-0.81). Ultrasound polyps size larger than 10 mm had an odds ratio (OR) of 8.147 (95%CI 2.56-23.40) for the presence of a^noma and malignancy, with a likelihood ratio of 2.78. CONCLUSIONS: There is a positive correlation and appropriate diagnostic accuracy between ultrasound size of gallbladder polyps compared to histopathological records, with a trend to overestimate the size by about 3 mm. Neoplastic polyps are uncommon, and it correlates with size. Polyps larger than 10 mm wee asociated with adenoma and malignancy. © 2023, Colegio Brasileiro de Cirurgia Digestiva. All rights reserved.

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Título según WOS: GALLBLADDER POLYPS: CORRELATION AND AGREEMENT BETWEEN ULTRASONOGRAPHIC AND HISTOPATHOLOGICAL FINDINGS IN A POPULATION WITH HIGH INCIDENCE OF GALLBLADDER CANCER
Título según SCOPUS: GALLBLADDER POLYPS: CORRELATION AND AGREEMENT BETWEEN ULTRASONOGRAPHIC AND HISTOPATHOLOGICAL FINDINGS IN A POPULATION WITH HIGH INCIDENCE OF GALLBLADDER CANCER; PÓLIPOS DA VESÍCULA BILIAR: CORRELAÇÃO E CONCORDÂNCIA ENTRE ACHADOS ULTRASSONOGRÁFICOS E HISTOPATOLÓGICOS EM UMA POPULAÇÃO COM ALTA INCIDÊNCIA DE CÂNCER DE VESÍCULA BILIAR.
Título de la Revista: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery
Volumen: 36
Editorial: Colegio Brasileiro de Cirurgia Digestiva
Fecha de publicación: 2023
Idioma: English
DOI:

10.1590/0102-672020230002e1732

Notas: ISI, SCOPUS