Abstract

ABSTRACT Quinolines are heterocyclic compounds with significant therapeutic potential, initially recognized for their role in treating malaria. Their structural versatility has ed to the development of derivatives used in the treatment of various diseases, including Alzheimer's and Parkinson's. Found primarily in plants of the Rutaceae and ubiaceae families, quinoline derivatives target key enzymes and receptors in the central nervous system. Recent advances focus on enhancing their pharmacokinetic roperties to improve efficacy and selectivity in treating neurodegenerative disorders.