ADAR-Mediated Regulation of Alternative Splicing as a Primary Driver of Breast Cancer Therapeutic Resistance

Armisen, Ricardo; Katherine Marcelain

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Fecha de publicación: 2026
Objetivos: To establish the ADAR1-splicing axis as a driver of resistance to a broad range of standard of care and novel breast cancer treatments, including cytotoxic, DNA damage-targeted therapies and splicing inhibitors, and to identify specific splice variants that are responsible for this resistance
Instrumento: Fondecyt Regular
Año de Inicio/Término: 2026-2029
Financiamiento/Sponsor: CONICYT
Rol del Usuario: INVESTIGADOR(A) ASOCIADO(A)
URL: https://www.cienciavida.org/
DOI:

1261427