Non-abortive effect of Adhatoda vasica spissum leaf extract by oral administration in rats

Burgos, R; Hancke, J; Wikman, G; Forcelledo M.; Croxatto H.; Wagner H.; MULLER, A

Abstract

The possible abortive effect of an extract of Adhatoda vasica leaf spissum, was studied in rats. The principal alkaloid detected in the extract was vasicine (0.85 ±0.03%). The extract (325 mg/kg/day) was administered with a gastric cannula to a group of 5 pregnant females between day 1 and 9 of pregnancy. In another experiment 9 pregnant females received in the water 0.25 and 2.5% of Adhatoda vasica between day 1 and 9 of pregnancy. It was concluded that the administration of Adhatoda vasica did not produce abortion in any of the treated groups.

Más información

Título de la Revista: PHYTOMEDICINE
Volumen: 4
Número: 2
Editorial: Elsevier GmbH
Fecha de publicación: 1997
Página de inicio: 145
Página final: 149
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0342619941&partnerID=q2rCbXpz