Total synthesis of annofolin

Vallejos G.; Rezende M.C.; Sepùlveda S.; Cassels, B.K.

Keywords: catalysis, spectroscopy, reduction, synthesis, extract, plant, proton, methylation, resonance, methyl, nuclear, carbon, infrared, drug, article, magnetic, alkaloid, 4, 1, dimethoxy, unclassified, 9,10, diacetoxy, azaanthracene, diethoxy, annofolin, annona, hayesii, cleistopholin

Abstract

The synthesis of annofolin (1), an alkaloid isolated from Annona hayesii in small amounts, by a phase-transfer catalytic reduction-methylation of cleistopholin (2) is reported, together with the preparation of its derivatives (3) and (4) by the same method.

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Título de la Revista: SYNTHETIC COMMUNICATIONS
Volumen: 29
Número: 5
Editorial: TAYLOR & FRANCIS INC
Fecha de publicación: 1999
Página de inicio: 809
Página final: 814
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0032996345&partnerID=q2rCbXpz