Article
JOURNAL OF NATURAL PRODUCTS  (1999)

Antibacterial diterpenoid acids from Azorella compacta

Wachter G.A.; Timmennann B.N.; Matooq G.; Hoffmann J.J.; Maiese W.M.; Singh M.P.; Montenegro,G.

Keywords: sensitivity, acid, isolation, antibacterial, tests, spectrum, plant, structure, agents, candida, diterpenoid, diterpenes, agent, coli, drug, molecular, article, albicans, staphylococcus, enterococcus, analysis, microbial, activity, faecium, aureus, relation, derivative, nonhuman, Escherichia, antiinfective, Anti-Bacterial, carboxylic, Anti-Infective, Spectral

Abstract

The two novel diterpenoid acids mulin-12,14-dien-11-on-20-oic acid (1) and mulin-12-ene-11,14-dion-20-oic acid (2) have been isolated from Azorella compacta. Their structures have been elucidated by 1D and 2D NMR methods. In contrast to the closely related known mulinolic acid (3) and its dehydration product (4) these new natural products have been shown to exhibit antimicrobial activity.

Más información

Título de la Revista: JOURNAL OF NATURAL PRODUCTS
Volumen: 62
Número: 9
Editorial: AMER CHEMICAL SOC
Fecha de publicación: 1999
Página de inicio: 1319
Página final: 1321
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0344564148&partnerID=q2rCbXpz