Risk factors for permanent kidney damage in children with urinary tract infection Factores de riesgo de daño renal permanente en niños con infección del tracto urinario.

Orellana P.; Cavagnaro F.; Baquedano, P; Lagomarsino, E; Garcia C.; Villarroel L.; Carreno, J.E.; Meneses L.

Keywords: age, distribution, infections, infection, kidney, risk, disease, regression, humans, diseases, human, male, reflux, recurrence, female, urinary, infant, article, child, factor, tract, analysis, recurrent, preschool, factors, studies, study, Child,, scintiscanning, Retrospective, vesicoureteral, Vesico-Ureteral

Abstract

BACKGROUND: In children, urinary tract infection (UTI) is a very common disease, and can cause permanent kidney damage. AIM: To determine risk factors for permanent kidney damage, in children with UTI. PATIENTS AND METHODS: In 337 children with UTI (237 female, mean age 4.2 years) a static renal scintigraphy was performed to assess the presence of permanent kidney damage. The history of vesicoureteral reflux and number of episodes of UTI was obtained. RESULTS: One hundred three children had a history of one episode of infection and the rest had recurrent infections. Permanent kidney damage was observed in 161 children (48%). This damage was observed in 39% of children of less than one year of age, in 43% of children aged 1 to 5 years of age and in 58% of children older than 5 years (p = 0.02). Sixty three percent of 122 children with vesicoureteral reflux had permanent kidney damage, compared with 27% of children without this condition (p < 0.001). Likewise, damage was observed in 36% of children with one episode of infection and 47% of children with recurrent infections (p < 0.01). No gender differences were observed. CONCLUSIONS: Vesicoureteral reflux, recurrence of UTI and age are associated with permanent renal damage in children with UTI.

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Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 130
Número: 10
Editorial: SOC MEDICA SANTIAGO
Fecha de publicación: 2002
Página de inicio: 1147
Página final: 1153
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036780438&partnerID=q2rCbXpz