Water-soluble cationic polymers and their polymer-metal complexes with bioacidal activity: A genotoxicity study

Rivas B.L; Pereira E.D.; Rivas R.J.; Saavedra M.A.; Mondaca M.A.

Keywords: silver, solubility, ions, polymerization, bacteria, weight, polyelectrolytes, synthesis, structure, bioassay, polyelectrolyte, copolymers, molecular, genotoxicity, activity, biocides, compounds, (chemical), bactericidal, (composition), Homopolymers

Abstract

Water-soluble polyelectrolytes containing ammonium and sulfonic groups, their polymer-Ag(I) complexes, and silver nitrate were investigated as bactericidal compounds for Staphylococcus aureus (Collection No. ATCC 28922) and Escherichia coli (Collection No. 6538P) according to the National Committee for Clinical Laboratory Standards (NCCL) method. All the compounds, except Ag(I), showed bactericidal activity only for S, aureus. Ag(I) showed high bactericidal activity for both bacteria. No important effect of the molecular weight or macromolecular size on the maximum bactericidal concentration value was observed. The genotoxicity was studied using the rec assay. None of the macromolecular compounds showed genotoxicity, except silver ions, whose value was borderline.

Más información

Título según SCOPUS: Water-soluble cationic polymers and their polymer-metal complexes with bioacidal activity: A genotoxicity study
Título de la Revista: JOURNAL OF APPLIED POLYMER SCIENCE
Volumen: 87
Número: 3
Editorial: Wiley
Fecha de publicación: 2002
Página de inicio: 452
Página final: 457
Idioma: English
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0037452099&partnerID=q2rCbXpz
DOI:

10.1002/app.11399

Notas: SCOPUS