Cytotoxic-antineoplastic activity of acetyl derivatives of prenylnaphthohydroquinone
Keywords: acid, survival, synthesis, cell, colon, structure, screening, proton, carcinoma, cytotoxicity, cancer, tumor, humans, lung, resonance, human, agents, nuclear, carbon, naphthoquinones, agent, drug, molecular, article, antitumor, hydroquinones, antineoplastic, activity, prenylnaphthohydroquinone, magnetic, controlled, hydroquinone, avarol, study, relationship, derivative, Structure-Activity, 50, Acetic, unclassified, Assays,, Line,, IC
Abstract
Several acetyl derivatives of prenylnaphthohydroquinone have been synthetised and evaluated for their cytotoxicity against A-549 human lung carcinoma and H-116 human colon carcinoma neoplastic cells. The IC50 values against A-549 are compared with those observed for previously reported unsubstituted derivatives. © 2004 Elsevier SAS. All rights reserved.
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Título según SCOPUS: | Cytotoxic-antineoplastic activity of acetyl derivatives of prenylnaphthohydroquinone |
Título de la Revista: | Farmaco |
Volumen: | 59 |
Número: | 8 |
Editorial: | Elsevier BV |
Fecha de publicación: | 2004 |
Página de inicio: | 651 |
Página final: | 656 |
Idioma: | English |
URL: | http://www.scopus.com/inward/record.url?eid=2-s2.0-3242708553&partnerID=q2rCbXpz |
DOI: |
10.1016/j.farmac.2004.03.005 |
Notas: | SCOPUS |