Solvent-free microwave synthesis of 3-(4-benzo[b]-thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-YL-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity
Abstract
A novel series of 2-benzothiophenealkylpiperazine derivatives 11 (a-d) with potential affinity at 5-HT1A serotonin receptors have been synthesized via solvent-free, microwave-promoted Michael addition of benzo[b]thiophene piperazine derivatives 6(a-c) to substituted benzo[b]thiophen-2-yl propenones 10(b,c). © 2008 The Japan Institute of Heterocyclic Chemistry.
Más información
Título según SCOPUS: | Solvent-free microwave synthesis of 3-(4-benzo[b]-thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-YL-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity |
Título de la Revista: | HETEROCYCLES |
Volumen: | 75 |
Número: | 8 |
Editorial: | PERGAMON-ELSEVIER SCIENCE LTD |
Fecha de publicación: | 2008 |
Página de inicio: | 1913 |
Página final: | 1929 |
URL: | http://www.scopus.com/inward/record.url?eid=2-s2.0-54049109725&partnerID=q2rCbXpz |
Notas: | SCOPUS |