Solvent-free microwave synthesis of 3-(4-benzo[b]-thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-YL-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity

Pessoa-Mahana H.; Kosche C. J.; Ron H. N.; Recabarren-Gajardo G.; Saitz B. C.; Araya-Maturana, R; Pessoa-Mahana C.D.

Abstract

A novel series of 2-benzothiophenealkylpiperazine derivatives 11 (a-d) with potential affinity at 5-HT1A serotonin receptors have been synthesized via solvent-free, microwave-promoted Michael addition of benzo[b]thiophene piperazine derivatives 6(a-c) to substituted benzo[b]thiophen-2-yl propenones 10(b,c). © 2008 The Japan Institute of Heterocyclic Chemistry.

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Título según SCOPUS: Solvent-free microwave synthesis of 3-(4-benzo[b]-thiophene-2-carbonyl)-1-piperazinyl-1-benzo[b]thiophen-2-YL-1-propanones. New hetero bis-ligands with potential 5-HT1A serotonergic activity
Título de la Revista: HETEROCYCLES
Volumen: 75
Número: 8
Editorial: PERGAMON-ELSEVIER SCIENCE LTD
Fecha de publicación: 2008
Página de inicio: 1913
Página final: 1929
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-54049109725&partnerID=q2rCbXpz
Notas: SCOPUS