Article
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS  (2012)

In vitro immunostimulant activity of the aromatic geranyl derivative Filifolinone Actividad inmunoestimulante in vitro del derivado aromático geranilado Filifolinona

Modak,B; Torres R.; Valenzuela,B; Imarai M.

Keywords: mouse, expression, antigen, flow, protein, cell, structure, maturation, mechanism, vitro, agent, female, drug, article, cytometry, class, controlled, animal, study, filifolinone, in, nonhuman, 2, major, unclassified, histocompatibility, dendritic, immunostimulating, immunostimulation

Abstract

The in vitro effect of the 3 H-spiro [1-benzofuran-2,1'-ciclohexane] derivative (Filifolinone), was evaluated on mouse dendritic cells through the level of expression of MHC molecules class II by flow cytometry. The results show that Filifolinone increases the expression of MHC promoting maturation of dendritic cells. The results suggest that Filifolinone is a potential immunomodulator for veterinary use.

Más información

Título de la Revista: BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS
Volumen: 11
Número: 3
Editorial: UNIV SANTIAGO CHILE CASA
Fecha de publicación: 2012
Página de inicio: 285
Página final: 290
URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84861766589&partnerID=q2rCbXpz