LOCATION, ORIENTATION AND DYNAMICS OF TWO MOLECULES WITH MITOCHONDRIAL ACTIVITY DISSOLVED IN ANIONIC LYOMESOPHASE: A ²H-NMR AND MD STUDY
Abstract
4,4-Dimethyl-5,8-dihydroanthracene-1,9,10(4H)-trione (Q1) and 9,10-Dihydroxy-4,4-dimethyl-5,8-dihydro-1(4H)-anthracenone (Q2), two molecules that inhibit cancer cell respiration, were selectively deuterated and dissolved in an anionic discotic nematic lyotropic liquid crystal (dnllc) solution. The solution provides a magnetic field oriented anisotropic medium, where the location, average orientation and dynamics of Q1 and Q2 were examined by measuring
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| Título según SCIELO: | LOCATION, ORIENTATION AND DYNAMICS OF TWO MOLECULES WITH MITOCHONDRIAL ACTIVITY DISSOLVED IN ANIONIC LYOMESOPHASE: A ²H-NMR AND MD STUDY |
| Título de la Revista: | JOURNAL OF THE CHILEAN CHEMICAL SOCIETY |
| Volumen: | 57 |
| Número: | 3 |
| Editorial: | SOC CHILENA QUIMICA |
| Fecha de publicación: | 2012 |
| Página de inicio: | 1295 |
| Página final: | 1300 |
| Idioma: | en |
| URL: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000300021&lng=en&nrm=iso&tlng=en |
| DOI: |
10.4067/S0717-97072012000300021 |
| Notas: | SCIELO |