LOCATION, ORIENTATION AND DYNAMICS OF TWO MOLECULES WITH MITOCHONDRIAL ACTIVITY DISSOLVED IN ANIONIC LYOMESOPHASE: A ²H-NMR AND MD STUDY
Abstract
4,4-Dimethyl-5,8-dihydroanthracene-1,9,10(4H)-trione (Q1) and 9,10-Dihydroxy-4,4-dimethyl-5,8-dihydro-1(4H)-anthracenone (Q2), two molecules that inhibit cancer cell respiration, were selectively deuterated and dissolved in an anionic discotic nematic lyotropic liquid crystal (dnllc) solution. The solution provides a magnetic field oriented anisotropic medium, where the location, average orientation and dynamics of Q1 and Q2 were examined by measuring
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Título según SCIELO: | LOCATION, ORIENTATION AND DYNAMICS OF TWO MOLECULES WITH MITOCHONDRIAL ACTIVITY DISSOLVED IN ANIONIC LYOMESOPHASE: A �H-NMR AND MD STUDY |
Título de la Revista: | Journal of the Chilean Chemical Society |
Volumen: | 57 |
Número: | 3 |
Editorial: | SOC CHILENA QUIMICA |
Fecha de publicación: | 2012 |
Página de inicio: | 1295 |
Página final: | 1300 |
Idioma: | en |
URL: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000300021&lng=en&nrm=iso&tlng=en |
DOI: |
10.4067/S0717-97072012000300021 |
Notas: | SCIELO |