Adiposidad visceral y su asociación con lípidos séricos e insulinemis en adolescentes obesas

Neri, Daniela; Espinoza, Aníbal; Bravo, Aurora; REBOLLO, M. JESÚS; Moraga, Francisco; Mericq, Veronica.; Castillo-Durán, Carlos

Abstract

"Background: Increased visceral or abdominal adipose tissue in children and adults is strongly associated with metabolic and a variety of chronic diseases. Aim: To study the association between visceral or external body measurements of adiposity with blood lipids, glucose and insulin levels, in obese female adolescents. Material and methods: In a cross-sectional study, 47 obese female adolescents (body mass index (BMI) >95th percentile) aged 10 to 15 years, were analyzed. Weight, height, BMI, Tanner pubertal stages, skinfold thickness, waist circumference, waist-to-hip ratio, fasting and 120 min post prandial blood glucose, serum insulin, and lipid profile were studied. Visceral fat was assessed by computed tomography at the L4-L5 level, measuring the fat area or the length of a straight drawn line between the spine and the internal border of the rectus abdominus muscle. Results: No association between lipid profile and BMI or external body measurements (skinfold thickness, waist circumference, waist-to-hip ratio) was observed. Total serum cholesterol >170 mg/dL was positively associated with the straight line over 63 mm (a cut-off obtained by ROC analysis (RR 2.64; 1.15-6.08). This association was statistically significant in girls in Tanner I + II (n =21; Fisher, p <0.023), but not with Tanner III + IV (n =26) stages. Increased cholesterol (>170 mg/dL) was also positively associated with a serum insulin >17 uU/mL in the Tanner I + II group (Fisher p<0.05), but not with the homeostasis model assessment of insulin resistance (HOMA). Conclusions: No external body measurement of adiposity was associated to increased serum cholesterol in these obese female adolescents. Increased total cholesterol (>170 mg/dL) was associated with visceral fat (evaluated through the straight line spina-rectus abdominus muscle), and also with a serum insulin >17 uU/ml in those teenagers with Tanner I or II pubertal stages"

Más información

Título según SCIELO: Adiposidad visceral y su asociación con lípidos séricos e insulinemis en adolescentes obesas
Título de la Revista: REVISTA MEDICA DE CHILE
Volumen: 135
Número: 3
Editorial: SOC MEDICA SANTIAGO
Fecha de publicación: 2007
Página de inicio: 294
Página final: 300
Idioma: es
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000300003&lng=en&nrm=iso&tlng=en
DOI:

10.4067/S0034-98872007000300003

Notas: SCIELO